protein phosphatase 2a — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1305	Ethoxysanguinarine	6-Ethoxydihydrosanguinarine	Apoptosis , AChR
	Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/-...		Apoptosis , AChR
T4449	LB100	LB-100,LB 100	Phosphatase
	LB100 (LB-100) is a water soluble protein phosphatase 2A (PP2A) inhibitor.		Phosphatase
T2068	(Rac)-LB-100		Phosphatase
	LB-100, a novel Protein Phosphatase 2A (PP2A) inhibitor, sensitizes malignant meningioma cells to the therapeutic effects of radiation		Phosphatase
T65086	Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride		Apoptosis , Phosphatase
	Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride may cause sensitization. Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride promotes apoptosis in HepG2 (IC50= 62 μM) and SK-Hep1 (IC50= 151 μM) cells and inhibits protein pho...		Apoptosis , Phosphatase
T2747	Endothall		Others
	Endothall is an effective protein phosphatase 2A (PP2A) inhibitor, exerting inhibitory effects on both PP2A and PP1, with IC50 values of 90 nM and 5 µM, respectively. It exhibits anticancer activity, making it suitable f...		Others
T35528L	TD52 dihydrochloride	TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl	Others
	TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signali...		Others
T15082	DDAO		Others
	DDAO is a promising near-infrared (NIR) red fluorescent probe with long emission wavelength (λem = 656 nm) and tunable excitation wavelength (600-650 nm). It can de desiged for detection of the activities of different en...		Others
T14859	Calyculin A	(-)-Calyculin A	Others
	Calyculin A is a potent and cell-permeable inhibitor of protein phosphatase 1 (PP1; IC50s: 2 nM). It also is a protein phosphatase 2A (PP2A) inhibitor (IC50s: 0.5-1 nM).		Others
T70725	Motuporin
	Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac).
T20153	FTY720-C2	FTY 720 C 2,FTY-720-C-2
	FTY720-C2 is an FTY720 analog. It acts as an effective stimulator of the activity of the protein phosphatase 2A.
T39239	TRC-766
	TRC-766, a negative control of RTC-5 (TRC-382), is a compound that exhibits protein phosphatase 2A (PP2A) binding properties while lacking phosphatase activation capabilities.
T31882	FTY720-Mitoxy	FTY 720 Mitoxy,FTY-720-Mitoxy
	FTY720-Mitoxy is an FTY720 analog that can be uesd as a novel stimulator of the activity of the protein phosphatase 2A (PP2A), targeting mitochondria.
T10060L	DT-061		Phosphatase
	DT-061 is an orally bioavailable protein phosphatase 2A (PP2A) activator. It could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis.		Phosphatase
T83530	LB-100
	(Rac)-LB-100 is the racemic form of the compound LB-100, which functions as an inhibitor of protein phosphatase 2A (PP2A) [1].
T35777	Nodularin
	The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatot...
T35806	N-Stearoylsphingosine	C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide	Phosphatase
	N-Stearoylsphingosine is an amide compound widely found in eukaryotic organisms that enhances protein phosphatase 2A (PP2A) activity by interfering with the binding of PP2A to PP2A inhibitor 2, leading to dephosphorylati...		Phosphatase
T82938	ATUX-1215
	ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70, GM-CSF, and IL1α in BLM-treated animals, potentially deceler...
T83938	TAT-PDHPS1
	TAT-PDHPS1 is a peptide inhibitor targeting Yes-associated protein (YAP) signaling, composed of the endogenous peptide PDHPS1 and the cell-penetrating peptide sequence TAT. It operates by binding to protein phosphatase 2...
T35613	Cytostatin (sodium salt)
	Cytostatin (sodium salt) is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectivel...
T37055	Cytostatin
	Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cel...